What operating systems is the mouse compatible with? Alex July 17, 2018 22:57 Updated Follow A. Windows 7, 8, 8.1, Vista, XP, Mac OS, Mac OS Mavericks and later. Requires one open USB port on computer. Related articles Instruction Guide Can this connect using Bluetooth? Why would you recommend this keyboard over other wireless bluetooth keyboards? What operating systems is the mouse compatible with? Drivers Comments 0 comments Please sign in to leave a comment.