What operating systems is the mouse compatible with? Alex December 15, 2020 19:16 Updated Follow A. Windows 7, 8, 8.1, Vista, XP, Mac OS, Mac OS Mavericks and later. Requires one open USB port on computer. Related articles Can this connect using Bluetooth? Instruction Guide Will I be able to use this mouse with Windows/PC? What operating systems is the mouse compatible with? Will the Mouse match my 2018 MacBook Air? Comments 0 comments Please sign in to leave a comment.