What operating systems is the mouse compatible with? Alex July 17, 2018 22:57 Updated Follow A. Windows 7, 8, 8.1, Vista, XP, Mac OS, Mac OS Mavericks and later. Requires one open USB port on computer. Related articles Can I replace the battery? Can I sync this to my iPad/iPhone? What operating systems is the mouse compatible with? Instruction Guide Drivers Comments 0 comments Please sign in to leave a comment.