What operating systems is the mouse compatible with? Alex July 17, 2018 22:57 Updated Follow A. Windows 7, 8, 8.1, Vista, XP, Mac OS, Mac OS Mavericks and later. Requires one open USB port on computer. Related articles Instruction Guide Can this connect using Bluetooth? What operating systems is the mouse compatible with? Will the Mouse match my 2018 MacBook Air? Do you I need to have a USB-C enabled computer to use this mouse? Comments 0 comments Please sign in to leave a comment.