Yes. The Mobile XR Hub with Audio has a 3.5mm audio jack that supports:

• 2.1 channel audio output
• Microphone input, including the built-in microphone on a headset
• Both CTIA and OMTP wiring standards, so it works with a wide range of wired headphones and headsets
• Built-in volume control

This makes it compatible with most 3.5mm wired headphones, speakers, and microphones.