Yes, the 4-Port USB-C Hub with PD can handle USB drives and external drives without performance degradation. Connecting external hard drives to all ports at once may cause disconnections, because of the power the drives need while transferring or downloading.

Power limits for connected devices:

• The maximum output voltage is 5V.
• A single connected device should not need more than 5V/2A.
• The USB-C data ports supply up to 5V/1.5A.

Eject any connected devices before disconnecting the hub from your host device.