No, the Aluminum Type-C Clamp Hub Pro is not confirmed to work with the late 2015 iMac. The Aluminum Type-C Clamp Hub Pro connects to the iMac with a USB-C cable that plugs into a Thunderbolt 3 (USB-C) port. Older iMacs do not have Thunderbolt 3 (USB-C) ports. Some older iMacs have Thunderbolt 2 ports, which are not the same as Thunderbolt 3.

The Aluminum Type-C Clamp Hub Pro is designed for 2017 iMac models with USB-C ports, including the 2017 iMac Pro, iMac Retina 4K, and 27-inch 5K models.

To see which devices Satechi has confirmed work with the Aluminum Type-C Clamp Hub Pro, see the Aluminum Type-C Clamp Hub Pro Device Compatibility article.